Panel designFunctions to optimize genomic region panels |
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Select mutations by maximal coverage |
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Reduce panel regions to input target ranges by respecting a minimum region size. |
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EvaluateFunctions for evaluating given panels |
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Get mapping of panel regions to covered patients and mutations. |
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Evaluate and annotate a given set of regions (panel) |
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Evaluate and annotate a given region to patient association data set |
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Mutation and rangesFunctions to work with mutation data and genomic ranges |
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Create GRanges object out of mutations |
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Create unique regions of fixed size around mutations as GRanges |
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Get all exons as GRanges object |
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DataToy example datasets |
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A toy example genomic ranges object. |
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A toy example data set linking patients to mutations. |
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A toy example data set linking patients to structural variants |